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产品目录

BCRP/ABCG2抗体图片
产品货号:
Z11535
中文名称:
BCRP/ABCG2抗体
英文名称:
Anti-BCRP/ABCG2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-BCRP/ABCG2 Antibody
指标别名ABC15;ABCG2;ABCP;BCRP;ABCG2;BMDP;CD338;CDw338;EST157481;MRX;MXR;MXR1
克隆性Polyclonal
检验物种mouse,rat
应用范围WB,IHC
基因名称ABCG2
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the C-terminal of human ABCG2(742-755aa,TIAYLKLLFLKKYS),identical to the related mouse and rat sequence.
实际分子量65~80KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料ABCG2(Atp-binding cassette,subfamily g,member 2) also known as ABCP,BCRP or MRX,is a protein that in humans is encoded by the ABCG2 gene.The ABCG2 gene encodes a membrane transporter belonging to the ATP-binding cassette(ABC) superfamily of membrane transporters,which are involved in the trafficking of biologic molecules across cell membranes.The ABCG2 protein is also a high capacity transporter for uric acid excretion in the kidney,liver,and gut.The ABCG2 gene is mapped on 4q22.1.In vitro assays of isolated membrane preparations revealed a high-capacity,vanadate-sensitive ATPase activity associated with ABCG2 expression that was stimulated by compounds known to be transported by this protein.Ozvegy et al.(2001)°Concluded that ABCG2 is likely functioning as a homodimer or homooligomer in this expression system since it is unlikely that putative Sf9 transport partners would be overexpressed at similarly high levels.Abcg2 transports pheophorbide-a,which occurs in various plant-derived foods and food supplements and is highly efficient in limiting its uptake from ingested food.ABCG2 is a major factor in the concentrative transfer of drugs,carcinogens,and dietary toxins to the milk of mice,cows,and humans.
Uniprot IDQ7TMS5
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称ATP-binding cassette,sub-family G(WHITE),member 2
蛋白名全称ATP-binding cassette sub-family G member 2
推荐稀释比
Western blot(WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:BCRP/ABCG2抗体BCRP抗体ABCG2多抗Anti-BCRP/ABCG2 Antibody
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